(±)-Hexanoylcarnitine chloride
CAS No. 6920-35-0
(±)-Hexanoylcarnitine chloride ( —— )
产品货号. M33766 CAS No. 6920-35-0
(±)-Hexanoylcarnitine chloride 是一种脂肪酸代谢产物,能将脂肪酸分解成能够被身体利用的能量。(±)-Hexanoylcarnitine chloride 还可作为大鼠骨骼肌毒性特异性且易于检测的生物标志物。在股骨直肌代谢组学分析中,Cerivastatin (HY-129458) 和 TMPD (HY-W012145) 可引起大鼠体内 Hexanoylcarnitine 增加。在 2 型糖尿病中,Hexanoylcarnitine 还与全因死亡率显著相关并可改善全因死亡率的预测。Hexanoylcarnitine 是识别新型致病途径的生物标志物。
纯度: >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| 规格 | 价格/人民币 | 库存 | 数量 |
| 2MG | ¥375 | 有现货 |
|
| 500MG | 获取报价 | 有现货 |
|
| 1G | 获取报价 | 有现货 |
|
生物学信息
-
产品名称(±)-Hexanoylcarnitine chloride
-
注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
-
产品简述(±)-Hexanoylcarnitine chloride 是一种脂肪酸代谢产物,能将脂肪酸分解成能够被身体利用的能量。(±)-Hexanoylcarnitine chloride 还可作为大鼠骨骼肌毒性特异性且易于检测的生物标志物。在股骨直肌代谢组学分析中,Cerivastatin (HY-129458) 和 TMPD (HY-W012145) 可引起大鼠体内 Hexanoylcarnitine 增加。在 2 型糖尿病中,Hexanoylcarnitine 还与全因死亡率显著相关并可改善全因死亡率的预测。Hexanoylcarnitine 是识别新型致病途径的生物标志物。
-
产品描述(±)-Hexanoylcarnitine chloride is a fatty acid metabolite that breaks down fatty acids into energy that can be used by the body. (±)-Hexanoylcarnitine chloride also serves as a specific and easily detectable biomarker for rat skeletal muscle toxicity. Cerivastatin (HY-129458) and TMPD (HY-W012145) induce an increase in Hexanoylcarnitine in rats in a metabolomic analysis of the rectus femoris muscle. In type 2 diabetes, Hexanoylcarnitine is also significantly associated with and improves prediction of all-cause mortality. Hexanoylcarnitine is a biomarker for the identification of novel pathogenic pathways.
-
体外实验——
-
体内实验——
-
同义词——
-
通路Metabolic Enzyme/Protease
-
靶点AChE
-
受体AChE
-
研究领域——
-
适应症——
化学信息
-
CAS Number6920-35-0
-
分子量295.8
-
分子式C13H26ClNO4
-
纯度>98% (HPLC)
-
溶解度In Vitro:?H2O 中的溶解度 : 250 mg/mL (845.17 mM; 超声助溶)
-
SMILES[Cl-].O=C(O)CC(OC(=O)CCCCC)C[N+](C)(C)C
-
化学全称——
运输与储存
-
储存条件(-20℃)
-
运输条件With Ice Pack
-
稳定性≥ 2 years
参考文献
1. Scarale MG, et al. Circulating Metabolites Associate With and Improve the Prediction of All-Cause Mortality in Type 2 Diabetes. Diabetes. 2022 Jun 1;71(6):1363-1370. ?
产品手册
关联产品
-
Dichlorvos
属于有机磷酸酯类化合物,是一种常用的环境卫生杀虫剂。
-
Rovatirelin
Rovatirelin (S-0373) is a newly synthesized thyrotropin-releasing hormone (TRH) analog that ameliorates cytosine arabinoside-induced motor dysfunction in a rat model of spinal cerebellar degeneration via acetylcholine and dopamine neurotransmission.
-
Rivastigmine tartrat...
一种乙酰胆碱酯酶抑制剂,可抑制丁酰胆碱酯酶和乙酰胆碱酯酶。
021-51111890
购物车()
sales@molnova.cn

